Nausea and vomiting of pregnancy in relation to smoking cigarettes in the current pregnancy
16. NAUSEA AND VOMITING OF PREGNANCY IN RELATION TO SMOKING CIGARETTES IN THE CURRENT PREGNANCY
- Smokers had significantly less NVP than non-smokers, 52% versus 79%. 210 patients. (38a)
- Nausea and vomiting of pregnancy (NVP) reported less frequently by women who were simultaneously both regular smokers and drinkers of alcohol, especially if these habits existed prior to pregnancy. (38b)
- Non-smokers are statistically more likely to have nausea and vomiting than smokers. 151 of the women studied were smokers, 500 in study. (27)
- There was a negative correlation between nausea and smoking. 855 singleton deliveries. (6)
- Women who smoked cigarettes had a lower median number of total hours of nausea compared to women who did not smoke (18 hours versus 45 hours Mann-Whitney U Test P=0.004). 363 women in study. (53)
- Smoking, and to a lesser extent alcohol intake, are related to a decreased risk of nausea and vomiting. 1,513 women in study. (45a)
- Women who gave up smoking during pregnancy reported more nausea and vomiting than those who continued to smoke. (45b)
- Smokers had lower scores than non-smokers for nausea and vomiting. The difference between the two groups approached significance. 100 women in the study. P=0.013. (48)
- Vomiting more likely to occur in non-smokers. Among women who never smoked, 58% vomited, whereas 46% of current smokers vomited. 4,517 women vomited, 3,502 did not. P
- Women with hyperemesis less likely to smoke in pregnancy. 78 women in study. (23)
- Women with hyperemesis gravidarum were less likely to smoke during pregnancy (O.R. = 0.6). 419 women with hyperemesis gravidarum. 836 who did not vomit. (22)
- Of 74 patients admitted with hyperemesis gravidarum, none were smokers. (28)
- Smoking was not associated with either nausea or vomiting during pregnancy or with scores on the overall nausea index. 160 women in study, 19 smoked cigarettes. (80)
- A risk factor for taking Meclozine by 16,536 women in the first 12 weeks of pregnancy was not to smoke. Meclozine was mainly taken for NVP. (133)
- Admission for HG
Smoking during pregnancy
Yes 261 21.4 Total admission for HG 1270
No 961 78.6 Total women in study 156,091 (158)
Nausea and vomiting of pregnancy including hyperemesis gravidarum more common in non-smokers. (6) (18) t (22) t (23) (27) (28) (38) ab(45) ab (48) (53) t (133) (158)
Total: Fourteen References
Smoking cigarettes not associated with NVP. (80) Total: One Reference
tP or O.R. value recorded.
Pooled population of pregnant women in 11 studies 29,937
BERNSTEIN L, PIKE MC, LOBO RA, DEPUE RH, ROSS RK, HENDERSON BE. Cigarette smoking in pregnancy damages placental cells.
Brit J. Obstet Gynaecol 1989:96;92-96.
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Please note this guideline is for moderate to severe NVP symptoms rather than HG
RCOG Green-top Guideline No. 69
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