HG and NVP after previous unsuccessful pregnancy...
25. HYPEREMESIS GRAVIDRAUM (HG) AND NAUSEA AND VOMITING IN PREGNANCY (NVP) AFTER PREVIOUS UNSUCCESSFUL PREGNANCY (MISCARRIAGE, STILLBIRTH OR NEONATAL DEATH)
- In no fewer than 41% of 207 HG patients is there a history of previous unsuccessful pregnancy. In a control population 1,719 cases (13.6%) gave a history of previous unsuccessful pregnancy. (10)
- Among 2,500 patients evaluated in the general clinic population there were 432 multiparas with previous abortions of whom 229 vomited (53.1%). Among the remaining 2,078 patients, 707 vomited (34%). The difference between these two percentages is statistically significant (t=7.3). (3)
- 86 women with hyperemesis gravidarum: the number of these women having a past history of abortion (24.4%) is much higher than would be expected from the general obstetric population (10%). (26)
- 27.4% - 52/190 women with hyperemesis gravidarum reported a spontaneous abortion in a previous pregnancy compared to 17.3% 36/209, in the control group (P
- Vomiting compared to non-vomiting was not more common among women experiencing prior fetal loss. 4,517 vomited, 3,502 did not vomit. (18)
- No obvious correlation between emesis gravidarum and a history of previous unsuccessful pregnancy (previous abortion, ectopic pregnancy, etc) was found. 62 women complained of NVP, 28 no NVP. (27)
- The numbers of previous pregnancies, miscarriages and terminations were not significant comparing those with the symptoms of NVP to those with no symptoms. 500 women, 380 had NVP. (27)
- No significant association between duration of nausea and previous miscarriage. 363 women, 292 had NVP. (53)
Increased NVP or HG associated with previous unsuccessful pregnancy.
(10) (3) (26) (64) t Three of these references refer to HG.
Total: Four References
Previous unsuccessful pregnancy not related to NVP. (18) (19) (27) (53)
Each of these references refers to NVP. Total: Four References
tP value recorded
Did you know?
Early access to treatments is likely to be more effective and may prevent symptoms developing into HG
Please note this guideline is for moderate to severe NVP symptoms rather than HG
RCOG Green-top Guideline No. 69
The Management of Nausea and Vomiting of Pregnancy and Hyperemesis Gravidarum
BMJ Clinical Update 2018
Management of severe pregnancy sickness and hyperemesis gravidarum
The risk of a baby being born with a congenital abnormality - the difference between relative and absolute risk
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09:29 17th February