HG and NVP after previous unsuccessful pregnancy...
25. HYPEREMESIS GRAVIDRAUM (HG) AND NAUSEA AND VOMITING IN PREGNANCY (NVP) AFTER PREVIOUS UNSUCCESSFUL PREGNANCY (MISCARRIAGE, STILLBIRTH OR NEONATAL DEATH)
- In no fewer than 41% of 207 HG patients is there a history of previous unsuccessful pregnancy. In a control population 1,719 cases (13.6%) gave a history of previous unsuccessful pregnancy. (10)
- Among 2,500 patients evaluated in the general clinic population there were 432 multiparas with previous abortions of whom 229 vomited (53.1%). Among the remaining 2,078 patients, 707 vomited (34%). The difference between these two percentages is statistically significant (t=7.3). (3)
- 86 women with hyperemesis gravidarum: the number of these women having a past history of abortion (24.4%) is much higher than would be expected from the general obstetric population (10%). (26)
- 27.4% - 52/190 women with hyperemesis gravidarum reported a spontaneous abortion in a previous pregnancy compared to 17.3% 36/209, in the control group (P
- Vomiting compared to non-vomiting was not more common among women experiencing prior fetal loss. 4,517 vomited, 3,502 did not vomit. (18)
- No obvious correlation between emesis gravidarum and a history of previous unsuccessful pregnancy (previous abortion, ectopic pregnancy, etc) was found. 62 women complained of NVP, 28 no NVP. (27)
- The numbers of previous pregnancies, miscarriages and terminations were not significant comparing those with the symptoms of NVP to those with no symptoms. 500 women, 380 had NVP. (27)
- No significant association between duration of nausea and previous miscarriage. 363 women, 292 had NVP. (53)
Increased NVP or HG associated with previous unsuccessful pregnancy.
(10) (3) (26) (64) t Three of these references refer to HG.
Total: Four References
Previous unsuccessful pregnancy not related to NVP. (18) (19) (27) (53)
Each of these references refers to NVP. Total: Four References
tP value recorded
Please note this guideline is for moderate to severe NVP symptoms rather than HG
RCOG Green-top Guideline No. 69
The Management of Nausea and Vomiting of Pregnancy and Hyperemesis Gravidarum
BMJ Clinical Update 2018
Management of severe pregnancy sickness and hyperemesis gravidarum
The risk of a baby being born with a congenital abnormality - the difference between relative and absolute risk
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