Effect of caffeine on nausea and vomiting of pregnancy



1.   The presence of nausea was associated with a tendency to decrease caffeine consumption. 59% of the nauseated controls decreased their consumption compared with 52% of non-nauseated controls. Similarly, 44% of the nauseated cases (women who had a spontaneous abortion) decreased their caffeine intake, compared to 36% of the non-nauseated cases. 607 women who had a miscarriage and 1,284 controls in study. (43)

2.   15% of women’s symptoms of NVP were worse after drinking tea or coffee. 363 women. (Gadsby - not published)

3.   Among those affected with aversions in pregnancy, there were dislike or a much reduced consumption of tea or coffee. 1,771 women in study. (41)

4.   Smell of coffee pots made NVP worse. (70)

5.   The second most aversive food category in pregnant women, particularly in the first trimester, was non-alcoholic beverages which included coffee and tea. (86)

6.   49 women, 28.8% of the 250 women in the study, decreased their intake of coffee in the first half of the pregnancy. About half of all women diminishing coffee consumption specifically cited a response to or provocation of nausea as an explanation. (71)

7.   Effective self care actions to reduce NVP cutting down on drinks of cola, tea, coffee, stated by 24% of 37 women. (102)

8.   Some women reported they were unable to tolerate coffee because it provoked their symptoms of NVP. 124 women returned completed clinical diaries. (108)

9.   Higher caffeine intake was only associated with lower risk of nausea and of nausea and vomiting in pregnancy. It is not possible to deduce from our data the casual nature of this association, whether women who drink caffeine do so because they have less nausea, or the higher caffeine intake itself reduces the risk of nausea. (P

10.   Avoidance of high caffeine sources is common among pregnant women although this is not necessarily associated with NVP. (96)

11.   Of 162 respondents, 26% (n = 41) stated a drink made NVP worse, of these 75.6% (n = 31), stated the drink was coffee.  (141)



Increased caffeine consumption makes NVP worse.

(43) Gadsby (41) (70) (86) (71) (102) (108) (141)               Total:   Nine References


Increased caffeine consumption associated with reduced NVP. (45) t

                                                                                              Total:   One Reference


Caffeine consumption not necessarily related to NVP. (96)   Total:   One Reference


t P value recorded. 


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