Age in relation to NVP
18. AGE IN RELATION TO NVP
- Vomiting compared to no vomiting was more common among younger women. Vomiting present in 69%, 54% and 38% of women aged less than 20, 20-34 and 35+ years respectively. 8,019 women, 4,517 vomited, 3,502 did not vomit. (18) t P
- Younger age was significantly associated with risk if hyperemesis gravidarum (HG). 419 women with HG, 836 women who did not vomit. (22)
- Younger age is significantly associated with an increased risk of hyperemesis gravidarum.
78 women in study. (23)
- The incidence of hyperemesis gravidarum is highest in the pregnant women between 21-25 years if age. 15,099 single pregnancies, 86 with hyperemesis gravidarum. (26)
- The greatest percentage of 87 HG patients occurred between age 21-25 years, 31%. (69)
- A shift towards younger women in HG. 3,068 women with HG. (29)
- A negative correlation was noted between the Rhodes INV scores and age, i.e the higher the score, the lower the age. 100 women. (48)
- Younger women were significantly (P=0.05) more likely to be nauseated than older women. 7,767 pregnancies. (51)
- Hyperemesis gravidarum is more prevalent among younger women. Average age HG 26.6 years. Average age controls 27.7 years, P
- The age of women who do not report morning sickness is significantly higher than in that of women with morning sickness. 6,376 pregnancies, 894 anti-emetics. (16)
- Younger women experience more severe episodes of morning sickness. 129 women in study. (77)
- Like others we found that the frequency of NP (nausea during pregnancy) decreased with age. 4,029 women in study. (67)
- 35 years and older was associated with decreased nausea (P
- NVP is not related to the patient’s age. 855 singleton deliveries. (6)
- Age is not related to the symptoms of hyperemesis gravidarum, 43 cases of vomiting of pregnancy admitted to hospital. (7)
- Nausea is not as common in the women between 25-29 years as in the younger and the older age groups. 90 women. (19)
- Age was found to have no statistical significance as far as comparing those with NVP to those with no NVP was concerned, 500 women, 120 no NVP. (27) t
- The mean age of 46 patients with severe hyperemesis, 26 patients with mild hyperemesis and a control group were not different. 8,802 in control group. (28)
- There was no significant correlation between the incidence of nausea with age. 1,000 women. (40)
- No significant correlation between NVP and age. 363 women. (53)
- Age was similar for those women who developed hyperemesis gravidarum, 193, and the general population. 13,053 women. (61)
- Greater maternal age did not produce a marked increase in risk of vomiting in the present study. 1,867 women with single live births, 1,666 no vomiting, 201 severe vomiting. (65)
- Age did not differ among the four groups.
Group 1: Those with no symptoms, 361 women.
Group 2: Those with nausea but no vomiting. 165 women.
Group 3: Those with vomiting. 922 women.
Group 4: Those with hyperemesis gravidarum. 5 women.
1,452 women with singleton pregnancies. (63)
- The woman’s age was not predictive of nausea and vomiting during pregnancy.
160 women in study. (80)
- There was a clear cut maternal age effect with a decline in the rate of NVP with age. The major increase in risk occurred in women aged younger than 25 years.
3,675 women in the study.
2,906 reported NVP. (132)
- Risk factors for taking Meclozine in early pregnancy. Young maternal age. This effect was possibly due to NVP. 16,536 women used Meclozine in the first 12 weeks of pregnancy. (133)
- Maternal age at delivery
Admissions for HG
20-29 yrs 823 64.8
30-34 yrs 226 17.8
35-49 yrs 68 5.4
Total number of admission for HG (n 1270) (158)
Women of younger age (up to 26 years) likely to have increased symptoms of NVP particularly hyperemesis gravidarum. 33,939 women in studies.
(18) (22) (23) (26) (69) (29) (48) (51) t (64) t (67) (77) (132) (133)
Total: Thirteen References
(Of this 13, the following refer to HG):- (22) (23) (26) (69) (29) (64)
Women of older age less likely to have NVP or HG (16) (31)(158) Total: Three References
Women’s age not related to NVP. 28,258 women in studies.
(6) (7) (19) (27) t (28) (40) (53) (61) (63) (65) (80) Total: Eleven References
(Of this 11, the following refer to HG):- (7) (28) (61) (63)
tP value recorded.
Please note this guideline is for moderate to severe NVP symptoms rather than HG
RCOG Green-top Guideline No. 69
The Management of Nausea and Vomiting of Pregnancy and Hyperemesis Gravidarum
BMJ Clinical Update 2018
Management of severe pregnancy sickness and hyperemesis gravidarum
The risk of a baby being born with a congenital abnormality - the difference between relative and absolute risk
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