Metoclopramide (Maxolon)
There is only limited information on its safety in pregnancy, although the little that has been published is reassuring. There are a very limited number of studies that indicate the effectiveness of metoclopramide in the treatment of nausea and vomiting in pregnancy. Side effects include drowsiness, restlessness and occasionally extra pyramidal effects (such as tremor, slurred speech, anxiety, distress and others). This is a prescription only medication.
It is used more commonly in America where the brand name is Reglan; the Food and Drug Administration (FDA) in America has recently recommended that it can be used for up to 12 weeks, but after this side effects can become more severe. There is further information about it at HelpHer.org
